NarL-phosphate must bind to multiple upstream sites to activate transcription from the narG promoter of Escherichia coli.

@article{Walker1994NarLphosphateMB,
  title={NarL-phosphate must bind to multiple upstream sites to activate transcription from the narG promoter of Escherichia coli.},
  author={M Susan Walker and John A. Demoss},
  journal={Molecular microbiology},
  year={1994},
  volume={14 4},
  pages={633-41}
}
The stimulation of Fnr-dependent transcription from the narG promoter by NarL-phosphate is known to require a cis-acting sequence, the NarL box, located approximately 195 bp upstream from the transcription start site, and the interaction of integration host factor (IHF) with a binding site in the intervening region (positions -110 to -140) between the NarL box and the transcription start site. By gel retardation and DNase I protection studies, we have demonstrated that NarL-phosphate, produced… CONTINUE READING
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