Napsins: new human aspartic proteinases. Distinction between two closely related genes.

@article{Tatnell1998NapsinsNH,
  title={Napsins: new human aspartic proteinases. Distinction between two closely related genes.},
  author={Peter J Tatnell and D. J. Powell and Jeffrey Hill and Todd S Smith and David G. Tew and John C. Kay},
  journal={FEBS letters},
  year={1998},
  volume={441 1},
  pages={
          43-8
        }
}
cDNA sequences were elucidated for two closely related human genes which encode the precursors of two hitherto unknown aspartic proteinases. The (pro)napsin A gene is expressed predominantly in lung and kidney and its translation product is predicted to be a fully functional, glycosylated aspartic proteinase (precursor) containing an RGD motif and an additional 18 residues at its C-terminus. The (pro)napsin B gene is transcribed exclusively in cells related to the immune system but lacks an in… CONTINUE READING
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