Naproxen. A reappraisal of its pharmacology, and therapeutic use in rheumatic diseases and pain states.

@article{Todd1990NaproxenAR,
  title={Naproxen. A reappraisal of its pharmacology, and therapeutic use in rheumatic diseases and pain states.},
  author={Peter A. Todd and Stephen P. Clissold},
  journal={Drugs},
  year={1990},
  volume={40 1},
  pages={
          91-137
        }
}
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) advocated for use in painful and inflammatory rheumatic and certain nonrheumatic conditions. It may be administered orally or rectally using a convenient once or twice daily regimen. Dosage adjustments are not usually required in the elderly or those with mild renal or hepatic impairment although it is probably prudent to start treatment at a low dosage and titrate upwards in such groups of patients. Numerous clinical trials have… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 45 CITATIONS

Naproxen/Esomeprazole Fixed-Dose Combination

  • Drugs & aging
  • 2011
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Renal Changes Associated with Naproxen Sodium Administration in Cynomolgus Monkeys

  • Toxicologic pathology
  • 1999
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 266 REFERENCES

Severe asthma after naproxen

R V.Lewis
  • Lancet I:
  • 1987
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Naproxen-associated aplastic anaemia

  • Medical Journal of Australia
  • 1986
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

Pulkk inen MO, Henz CMR. The eITect of naproxensodium on the intrauterine pressure and menstrual pain of dysmenorrhoeic patients

AI Csapo
  • Prostaglandins
  • 1977
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

A safety profile of controlled release naproxen tablets.

  • The New Zealand medical journal
  • 1989
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Pharmacokinetics of naproxen sodium.

  • Cephalalgia : an international journal of headache
  • 1986
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

[Piroxicam and naproxen in acute soft tissue injuries].

  • Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
  • 1986
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Evaluation of the pharmacokinetics of naproxen from a 500mg controlled-release tablet

A Cohen, MA Ganzalez, EJ Mroszezak, J. Yee
  • Current Therapeutic Research
  • 1988
VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL