Nanovehicles as a novel target strategy for hyperthermic intraperitoneal chemotherapy: a multidisciplinary study of peritoneal carcinomatosis

@inproceedings{Nowacki2015NanovehiclesAA,
  title={Nanovehicles as a novel target strategy for hyperthermic intraperitoneal chemotherapy: a multidisciplinary study of peritoneal carcinomatosis},
  author={Maciej Nowacki and Marek Wiśniewski and Karolina Werengowska-Cie{\'c}wierz and Katarzyna Roszek and Joanna Czarnecka and Iwona Łakomska and Tomasz Kloskowski and Dominik Janusz Tyloch and Robert Debski and Katarzyna Pietkun and Marta Pokrywczyńska and Dariusz Grzanka and Rafał Czajkowski and Gerard Drewa and Arkadiusz Jundziłł and Joseph K. Agyin and Samy L Habib and Artur P. Terzyk and Tomasz Drewa},
  booktitle={Oncotarget},
  year={2015}
}

• Maciej Nowacki, Marek Wiśniewski, +16 authors Tomasz Drewa
• Published 2015 in Oncotarget

In general, detection of peritoneal carcinomatosis (PC) occurs at the late stage when there is no treatment option. In the present study, we designed novel drug delivery systems that are functionalized with anti-CD133 antibodies. The C1, C2 and C3 complexes with cisplatin were introduced into nanotubes, either physically or chemically. The complexes were reacted with anti-CD133 antibody to form the labeled product of A0-o-CX-chem-CD133. Cytotoxicity screening of all the complexes was performed… CONTINUE READING

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