Nanotechnologies for biomolecular detection and medical diagnostics.

  title={Nanotechnologies for biomolecular detection and medical diagnostics.},
  author={Mark Ming-Cheng Cheng and Giovanni Cuda and Yuri L Bunimovich and Marco Gaspari and James R. Heath and Haley D Hill and Chad A. Mirkin and A Jasper Nijdam and Rosa Terracciano and Thomas G. Thundat and Mauro Ferrari},
  journal={Current opinion in chemical biology},
  volume={10 1},
Nanotechnology-based platforms for the high-throughput, multiplexed detection of proteins and nucleic acids in heretofore unattainable abundance ranges promise to bring substantial advances in molecular medicine. The emerging approaches reviewed in this article, with reference to their diagnostic potential, include nanotextured surfaces for proteomics, a two-particle sandwich assay for the biological amplification of low-concentration biomolecular signals, and silicon-based nanostructures for… CONTINUE READING

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