Nanosuspensions as advanced printing ink for accurate dosing of poorly soluble drugs in personalized medicines.

@article{Pardeike2011NanosuspensionsAA,
  title={Nanosuspensions as advanced printing ink for accurate dosing of poorly soluble drugs in personalized medicines.},
  author={Jana Pardeike and Daniela M Strohmeier and Nina Schr{\"o}dl and Christine Voura and Michael Gruber and Johannes G. Khinast and Andreas Zimmer},
  journal={International journal of pharmaceutics},
  year={2011},
  volume={420 1},
  pages={93-100}
}
Folic acid was used as a model drug to demonstrate the advantages of formulating poorly soluble drugs as nanosuspensions and their use in an inkjet-type printing technique to produce personalized medicines. 10% folic acid nanosuspensions stabilized with Tween 20, a stabilizer showing the best wetting potential for folic acid, were prepared via high pressure homogenization. The particle size of the folic acid nanosuspension was well below 5 μm being a prerequisite for inkjet type printing… CONTINUE READING

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