Nanostructured porous polymer monolithic columns for capillary liquid chromatography of peptides.


The macroporous structure of poly(styrene-co-divinylbenzene) monolithic capillary columns has been optimized for the gradient separation of peptides. To exploit monolithic supports with porosity exceeding 70%, the thermodynamic properties of the polymerization mixture were carefully tailored to yield homogeneous monolithic materials featuring macropore and… (More)
DOI: 10.1016/j.chroma.2014.11.063