Nanostructured ceramics in medical devices: Applications and prospects

  title={Nanostructured ceramics in medical devices: Applications and prospects},
  author={Roger J. Narayan and Prashant N. Kumta and Charles Sfeir and Donghyun Lee and Daiwon Choi and Dana Olton},
Nanostructured materials may possess unique capabilities for specific interactions with cells, proteins, and DNA. This article reviews several classes of nanostructured ceramics with unique biological functionalities that are being considered for use in medical devices. The properties of calcium phosphate nanoparticles (Nano-CaPs™) and diamond-like carbon-metal nanocomposite films are described in detail. 

Biomedical applications of ceramic nanocomposites

Abstract: Bioceramics and bioceramic composites have been widely used for biomedical applications for the last 50 years. This chapter discusses the advantages of using ceramic nanocomposites. The

Synthesis and application of nanostructured calcium phosphate ceramics for bone regeneration.

Because crystallographic and chemical studies have shown that synthetic hydroxyapatite closely resembles the inorganic phase found in bone and teeth, synthesis and applications of nanostructured calcium phosphate ceramics have been reviewed.

Laser Processing of Advanced Bioceramics

In this article, laser processing of diamondlike carbon‐metal nanocomposite films, hydroxyapatite‐osteoblast composites, and Ormocer® microdevices for medical applications is described. Pulsed laser

Review of Bionanocomposite Coating Films and Their Applications

This review provides an in-depth discussion on the properties and applications of biopolymer-based nanocomposite coating films.

Hydroxyapatite/diamondlike carbon nanocomposites : A novel surface modification to extend orthopaedic prosthesis lifetimes

Conventional plasma-sprayed hydroxyapatite coatings suffer from many difficulties that have limited their use in orthopaedic implants, including uneven resorption rates, poor fracture toughness, and

Pulsed Laser Deposition of Hydroxyapatite Thin Films

Mechanical properties of dispersed ceramic nanoparticles in polymer composites for orthopedic applications

  • H. LiuT. Webster
  • Materials Science, Engineering
    International journal of nanomedicine
  • 2010
It is demonstrated that the combination of PLGA with well-dispersed nanoceramics enhanced mechanical properties necessary for load-bearing orthopedic/dental applications.

Biomaterials and Biotechnology Schemes Utilizing TiO2 Nanotube Arrays

Here it is revealed how the TiO2 surface nanoconfigurations are advantageous in various tissue engineering and regenerative medicine applications, for osteo-chondral, orthopedic, and ostee-progenitor implant applications discussed here and beyond.

Effect of proteins on the synthesis and assembly of calcium phosphate nanomaterials.

This paper reviews the examples of templates based on proteins and polypeptides that have been successfully employed to manufacture calcium phosphate nanomaterials and focuses on recent advances in the synthesis of calcium phosphate materials by taking advantage of protein assemblies.

Bio‐Inspired Enamel Repair via Glu‐Directed Assembly of Apatite Nanoparticles: an Approach to Biomaterials with Optimal Characteristics

As the outermost layer, enamel is susceptible to caries due to the products of bacteria metabolism or acidic foods. [ 4 ] It is critically serious that the enamel damage is permanent. [ 4 ] Different



Nanostructure Processing of Hydroxyapatite-based Bioceramics

Nanostructure processing was applied to derive hydroxyapatite and hydroxyapatite-zirconia bioceramics with ultrafine microstructures and significantly improved mechanical properties for orthopedic

Fabrication of Nanomaterials Using Porous Alumina Templates

Nanofabrication by self-organization methods has attracted much attention owing to the fact that it enables mass production without the use of expensive lithographical tools, such as an electron beam

Engineering analysis of diamond-like carbon coated polymeric materials for biomedical applications.

DLC films appear to be promising candidates for biomedical applications and merit investigation, according to the evaluation of surface properties by many methods and measurements.

Hydroxylapatite synthesis and characterization in dense polycrystalline form

A new process is described for preparing dense, polycrystalline hydroxylapatite. This material has close to theoretical density and is free of fine pores and second phases. The best material has an

Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics.

Select enhanced osteoblast adhesion was independent of surface chemistry and material phase but was dependent on the surface topography (specifically on grain and pore size) of nanophase ceramics.