Nanostructured Polymeric Micelles Carrying Xanthene Dyes for Photodynamic Evaluation.

  title={Nanostructured Polymeric Micelles Carrying Xanthene Dyes for Photodynamic Evaluation.},
  author={Camila Fabiano de Freitas and Diogo Silva Pellosi and Bianca Martins Estev{\~a}o and Italo Rodrigo Calori and Tayana Mazin Tsubone and M{\'a}rio Jos{\'e} Politi and Wilker Caetano and Noboru Hioka},
  journal={Photochemistry and photobiology},
  volume={92 6},
It was evaluated the properties of the xanthene dyes Erythrosin B, Eosin Y and theirs Methyl, Butyl and Decyl ester derivatives as possible photosensitizers (PS) for photodynamic treatments. The more hydrophobic dyes self-aggregate in water/ethanol solutions above 70% water (vol/vol) in the mixture. In buffered water, these PS were encapsulated in Pluronic polymeric surfactants of P-123 and F-127 by two methodologies: direct addition and the thin-film solid dispersion methods. The thin-film… CONTINUE READING

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