Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering

@inproceedings{Silva2013Nanostructured3C,
  title={Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering},
  author={Joana Margarida Silva and Nicole Georgi and Rui M Costa and Praveen Sher and Rui Lu{\'i}s Reis and Clemens A van Blitterswijk and Marcel Karperien and Jo{\~a}o F Mano},
  booktitle={PloS one},
  year={2013}
}
Nanostructured three-dimensional constructs combining layer-by-layer technology (LbL) and template leaching were processed and evaluated as possible support structures for cartilage tissue engineering. Multilayered constructs were formed by depositing the polyelectrolytes chitosan (CHT) and chondroitin sulphate (CS) on either bidimensional glass surfaces or 3D packet of paraffin spheres. 2D CHT/CS multi-layered constructs proved to support the attachment and proliferation of bovine chondrocytes… CONTINUE READING
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