Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse.

@article{Shin2010NanosizedTD,
  title={Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse.},
  author={Jin A. Shin and Eun Jeong Lee and Scott M. Seo and Hee Sun Kim and Jihee Lee Kang and E M Park},
  journal={Neuroscience},
  year={2010},
  volume={165 2},
  pages={445-54}
}
Nanosized titanium dioxide (TiO(2)) is used widely in various everyday products and can be applied to the medical field for diagnostic or therapeutic tools. However, its neurobiological responses have not been defined completely in the brain. To evaluate the acute inflammatory response to TiO(2) particles of two different sizes in normal and septic brains, male C57BL/6 mice were given intraperitoneal injections of fine (<1 microm) or ultrafine (21 nm) TiO(2), 30 min after vehicle or… CONTINUE READING