Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency.

Abstract

There is currently an unmet need for the supply of autologous, patient-specific stem cells for regenerative therapies in the clinic. Mesenchymal stem cell differentiation can be driven by the material/cell interface suggesting a unique strategy to manipulate stem cells in the absence of complex soluble chemistries or cellular reprogramming. However, so far… (More)
DOI: 10.1038/nmat3058

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