Nanoscale manipulation of membrane curvature for probing endocytosis in live cells.

@article{Zhao2017NanoscaleMO,
  title={Nanoscale manipulation of membrane curvature for probing endocytosis in live cells.},
  author={Wenting Zhao and Lindsey Hanson and Hsin-Ya Lou and Matthew Akamatsu and Praveen D. Chowdary and Francesca Santoro and Jessica R. Marks and Alexandre Grassart and David G Drubin and Yi Cui and Bianxiao Cui},
  journal={Nature nanotechnology},
  year={2017},
  volume={12 8},
  pages={
          750-756
        }
}
Clathrin-mediated endocytosis (CME) involves nanoscale bending and inward budding of the plasma membrane, by which cells regulate both the distribution of membrane proteins and the entry of extracellular species. Extensive studies have shown that CME proteins actively modulate the plasma membrane curvature. However, the reciprocal regulation of how the plasma membrane curvature affects the activities of endocytic proteins is much less explored, despite studies suggesting that membrane curvature… CONTINUE READING

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