Nanoscale characterization of acid and thermally treated collagen fibrils.

Abstract

Type I collagen is a major extracellular matrix component and its hierarchical structure plays an essential role in the regulation of cellular behavior. Here, we have analyzed the changes in the morphological, chemical, and mechanical properties of collagen fibrils induced by acidic and thermal treatments and the influence on the cellular response of MC3T3… (More)
DOI: 10.1016/j.actbio.2012.05.029

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