Nanoscale bioactive glass activates osteoclastic differentiation of RAW 264.7 cells.

@article{Detsch2016NanoscaleBG,
  title={Nanoscale bioactive glass activates osteoclastic differentiation of RAW 264.7 cells.},
  author={Rainer Detsch and Matthias Ruebner and Pamela L. Strissel and Dirk Mohn and Erwin F. Strasser and Wendelin J Stark and Reiner Strick and Aldo R Boccaccini},
  journal={Nanomedicine},
  year={2016},
  volume={11 9},
  pages={1093-105}
}
BACKGROUND There is limited knowledge regarding differentiation of osteoclasts in the presence of nanoscale bioactive glass (nBG). This investigation examined increasing concentrations of 45S5 nBG and their influence on osteoclast differentiation. MATERIALS & METHODS Different concentrations of 45S5 nBG were cultured up to 14 days with the murine RAW264.7 cell line and human primary monocytes cultured with M-CSF and RANKL. RESULTS Culturing cells for 14 days with 500 μg/ml nBG showed a… CONTINUE READING

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