Nanoscale-alumina induces oxidative stress and accelerates amyloid beta (Aβ) production in ICR female mice.

Abstract

The adverse effects of nanoscale-alumina (Al2O3-NPs) have been previously demonstrated in both in vitro and in vivo studies, whereas little is known about their mechanism of neurotoxicity. It is the goal of this research to determine the toxic effects of nano-alumina on human neuroblastoma SH-SY5Y and mouse hippocampal HT22 cells in vitro and on ICR female… (More)
DOI: 10.1039/c5nr03598h

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