Nanoscale X-ray microscopic imaging of mammalian mineralized tissue.

  title={Nanoscale X-ray microscopic imaging of mammalian mineralized tissue.},
  author={Joy Cooke Andrews and Eduardo de Almeida and Marjolein C H van der Meulen and Joshua S. Alwood and Chialing Lee and Yijin Liu and Jie Chen and Florian Meirer and Michael Feser and Jeff Gelb and Juana Rudati and Andrei Tkachuk and Wenbing Yun and Piero A. Pianetta},
  journal={Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada},
  volume={16 3},
A novel hard transmission X-ray microscope (TXM) at the Stanford Synchrotron Radiation Lightsource operating from 5 to 15 keV X-ray energy with 14 to 30 microm2 field of view has been used for high-resolution (30-40 nm) imaging and density quantification of mineralized tissue. TXM is uniquely suited for imaging of internal cellular structures and networks in mammalian mineralized tissues using relatively thick (50 microm), untreated samples that preserve tissue micro- and nanostructure. To test… CONTINUE READING