Nanoprecipitation for Poorly Water-Soluble Drugs.

  title={Nanoprecipitation for Poorly Water-Soluble Drugs.},
  author={Tuong Ngoc-Gia Nguyen and Van-Thanh Tran and W. Duan and Phuong Ha-Lien Tran and Thao Truong-Dinh Tran},
  journal={Current drug metabolism},
  volume={18 11},
BACKGROUND More than 60% of the active pharmaceutical ingredients, which are classified as Biopharmaceutics Classification System class II. The limited solubility of these drug may lead to low therapeutic effects. METHODS Nanoprecipitation presents some advantages because it is a straightforward method with low-cost equipment that is easy to scale up. RESULTS However, there are two technical issues of concern related to this method. First, the two solvents used for this approach must be… CONTINUE READING