Nanopore sequencing data analysis: state of the art, applications and challenges.

@article{Magi2017NanoporeSD,
  title={Nanopore sequencing data analysis: state of the art, applications and challenges.},
  author={Alberto Magi and Roberto Semeraro and Alessandra Mingrino and Betti Giusti and Romina D'Aurizio},
  journal={Briefings in bioinformatics},
  year={2017}
}
The nanopore sequencing process is based on the transit of a DNA molecule through a nanoscopic pore, and since the 90s is considered as one of the most promising approaches to detect polymeric molecules. In 2014, Oxford Nanopore Technologies (ONT) launched a beta-testing program that supplied the scientific community with the first prototype of a nanopore sequencer: the MinION. Thanks to this program, several research groups had the opportunity to evaluate the performance of this novel… CONTINUE READING
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