Nanopore analytics: sensing of single molecules.

@article{Howorka2009NanoporeAS,
  title={Nanopore analytics: sensing of single molecules.},
  author={Stefan Howorka and Zuzanna S Siwy},
  journal={Chemical Society reviews},
  year={2009},
  volume={38 8},
  pages={
          2360-84
        }
}
In nanopore analytics, individual molecules pass through a single nanopore giving rise to detectable temporary blockades in ionic pore current. Reflecting its simplicity, nanopore analytics has gained popularity and can be conducted with natural protein as well as man-made polymeric and inorganic pores. The spectrum of detectable analytes ranges from nucleic acids, peptides, proteins, and biomolecular complexes to organic polymers and small molecules. Apart from being an analytical tool… CONTINUE READING
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