Nanopore Sequencing of a Forensic STR Multiplex Reveals Loci Suitable for Single-Contributor STR Profiling

@article{Tytgat2020NanoporeSO,
  title={Nanopore Sequencing of a Forensic STR Multiplex Reveals Loci Suitable for Single-Contributor STR Profiling},
  author={O. Tytgat and Y. Gansemans and Jana Weymaere and Kaat Rubben and D. Deforce and F. van Nieuwerburgh},
  journal={Genes},
  year={2020},
  volume={11}
}
Nanopore sequencing for forensic short tandem repeats (STR) genotyping comes with the advantages associated with massively parallel sequencing (MPS) without the need for a high up-front device cost, but genotyping is inaccurate, partially due to the occurrence of homopolymers in STR loci. The goal of this study was to apply the latest progress in nanopore sequencing by Oxford Nanopore Technologies in the field of STR genotyping. The experiments were performed using the state of the art R9.4… Expand
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