Nanoparticles with entrapped α-tocopherol: synthesis, characterization, and controlled release.

@article{Zigoneanu2008NanoparticlesWE,
  title={Nanoparticles with entrapped α-tocopherol: synthesis, characterization, and controlled release.},
  author={Imola Gabriela Zigoneanu and Carlos E Astete and Cristina M Sabliov},
  journal={Nanotechnology},
  year={2008},
  volume={19 10},
  pages={105606}
}
An emulsion evaporation method was used to synthesize spherical poly(DL-lactide-co-glycolide) (PLGA) nanoparticles with entrapped α-tocopherol. Two different surfactants were used: sodium dodecyl sulfate (SDS) and poly(vinyl alcohol) (PVA). For SDS nanoparticles, the size of the nanoparticles decreased significantly with the entrapment of α-tocopherol in the PLGA matrix, while the size of PVA nanoparticles remained unchanged. The polydispersity index after synthesis was under 0.100 for PVA… CONTINUE READING
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