Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection.

  title={Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection.},
  author={Y. Charles Cao and Rongchao Jin and Chad A. Mirkin},
  volume={297 5586},
Multiplexed detection of oligonucleotide targets has been performed with gold nanoparticle probes labeled with oligonucleotides and Raman-active dyes. The gold nanoparticles facilitate the formation of a silver coating that acts as a surface-enhanced Raman scattering promoter for the dye-labeled particles that have been captured by target molecules and an underlying chip in microarray format. The strategy provides the high-sensitivity and high-selectivity attributes of gray-scale scanometric… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 341 extracted citations

A Theoretical and Experimental Study of DNA Self-assembly by Harish Chandran

Harish Chandran, Supervisor Thomas LaBean Chris Dwyer Kamesh Munagala
View 5 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-2 of 2 references


L. A. Gearheart, H. J. Ploehn, C. J. Murphy, J. Phys
B. 105, • 1260
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…