Nanoparticles for drug delivery in cancer treatment.

  title={Nanoparticles for drug delivery in cancer treatment.},
  author={Barbara B. Haley and Eugene Frenkel},
  journal={Urologic oncology},
  volume={26 1},
Nanoparticles (size in nanometer range) provide a new mode of cancer drug delivery functioning as a carrier for entry through fenestrations in tumor vasculature allowing direct cell access. These particles allow exquisite modification for binding to cancer cell membranes, the microenvironment, or to cytoplasmic or nuclear receptor sites. This results in delivery of high drug concentrations to the targeted cancer cell, with reduced toxicity of normal tissue. Several such engineered drugs are in… CONTINUE READING
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