Nanoparticles as Titanium Coatings: A Valuable Strategy to Prevent Implant- associated Infections

  title={Nanoparticles as Titanium Coatings: A Valuable Strategy to Prevent Implant- associated Infections},
  author={Elvira De Giglio and Adriana Trapani and Damiana Cafagna and Concetta Ferretti and Roberta Iatta and Stefania Cometa and Edmondo Ceci and Antonella Romanelli and Monica Mattioli-Belmonte},
Orthopaedic infections represent one of the major causes of implant failure. Systemic treatment is limited due to dosing, side-effects, patient compliance, treatment length and resistant bacteria. The choice of antibiotic incorporation method has been the subject of many investigations and, nowadays, various vehicles for local drug delivery have been studied. In this work, a novel ciprofloxacin loaded chitosan nanoparticles coating system onto titanium surface has been developed and… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 26 references

Drug loaded thermoresponsive and cytocompatible chitosan based hydrogel as a potential wound dressing, Carbohyd Polym

C. Radhakumary, A. Molly, K Sreenivasan

A comparative study of chitosan and chitosan/cyclodextrin nanoparticles as potential carriers for the oral delivery of small peptides.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V • 2010

Antibacterial hydrogel and use thereof in orthopedics

G. Giammona, G. Pitarresi, +3 authors E. Cremascoli
Patent Cooperation Treaty Application, • 2010

Cell behaviour on bioactive polymeric coatings.

Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia • 2010