Nanoparticle-mediated measurement of target-drug binding in cancer cells.


Responses to molecularly targeted therapies can be highly variable and depend on mutations, fluctuations in target protein levels in individual cells, and drug delivery. The ability to rapidly quantitate drug response in cells harvested from patients in a point-of-care setting would have far reaching implications. Capitalizing on recent developments with… (More)
DOI: 10.1021/nn203450p


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