Nanoparticle mediated chemotherapy of hormone refractory prostate cancer with a novel combi-molecule.

Abstract

In previous study, we synthesized a novel combi-molecule, JDF-12, with superior cytotoxicity against prostate cancer cells, but it has a poor stability in liquid after preparation with traditional method and is susceptible to hydrolysis and binding to organs highly expressing epidermal growth factor receptor (EGFR), resulting in side effects. In this study… (More)

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@article{Fang2015NanoparticleMC, title={Nanoparticle mediated chemotherapy of hormone refractory prostate cancer with a novel combi-molecule.}, author={You-qiang Fang and Jie-ying Wu and Teng-Cheng Li and Wei Liu and Li Gao and Yun Luo}, journal={American journal of translational research}, year={2015}, volume={7 8}, pages={1440-9} }