Nanoparticle diffusion in sheared cellular blood flow

  title={Nanoparticle diffusion in sheared cellular blood flow},
  author={Zixiang Liu and Jonathan R. Clausen and Rekha Ranjana Rao and Cyrus K. Aidun},
  journal={Journal of Fluid Mechanics},
  pages={636 - 667}
Using a multiscale blood flow solver, the complete diffusion tensor of nanoparticles (NPs) in sheared cellular blood flow is calculated over a wide range of shear rate and haematocrit. In the short-time regime, NPs exhibit anomalous dispersive behaviors under high shear and high haematocrit due to the transient elongation and alignment of the red blood cells (RBCs). In the long-time regime, the NP diffusion tensor features high anisotropy. Particularly, there exists a critical shear rate… 

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  • Hong ZhaoE. Shaqfeh
  • Physics
    Physical review. E, Statistical, nonlinear, and soft matter physics
  • 2011
The lateral migration of platelets in a microchannel is studied numerically where the hydrodynamic interactions between red cells, platelets, and vessel walls are resolved by the Stokes flow boundary integral equations and the lateral migration is shown to be diffusional.