Nanoparticle delivery of donor antigens for transplant tolerance in allogeneic islet transplantation.

@article{Bryant2014NanoparticleDO,
  title={Nanoparticle delivery of donor antigens for transplant tolerance in allogeneic islet transplantation.},
  author={Jane E Bryant and Kelan A Hlavaty and Xiaomin Zhang and Woon-Teck Yap and Lei Zhang and Lonnie D Shea and Xunrong Luo},
  journal={Biomaterials},
  year={2014},
  volume={35 31},
  pages={8887-8894}
}
Human islet cell transplantation is a promising treatment for type 1 diabetes; however, long-term donor-specific tolerance to islet allografts remains a clinically unmet goal. We have previously shown that recipient infusions of apoptotic donor splenocytes chemically treated with 1-ethyl-3-(3'-dimethylaminopropyl)-carbodiimide (donor ECDI-SP) can mediate long-term acceptance of full major histocompatibility complex (MHC)-mismatched murine islet allografts without the use of immunosuppression… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Similar Papers

Loading similar papers…