Nanoparticle-coated microparticles: preparation and characterization.

  title={Nanoparticle-coated microparticles: preparation and characterization.},
  author={Ruy Carlos Ruver Beck and Adriana Raffin Pohlmann and S{\'i}lvia Stanisçuaski Guterres},
  journal={Journal of microencapsulation},
  volume={21 5},
The objective of the present work was to design and prepare new nanoparticle-coated drug-loaded inorganic microparticles by spray-drying using diclofenac as drug model. Previous works presented the process to dry drug-loaded polymeric nanoparticles using silicon dioxide as adjuvant, otherwise in the present proposition the drug is associated with the silicon dioxide and unloaded polymeric nanocapsule or nanosphere suspensions were used as organic coating. Eudragit S100 was chosen because of its… CONTINUE READING