Nanoparticle applications in ocular gene therapy

  title={Nanoparticle applications in ocular gene therapy},
  author={Xue Cai and Shannon M Conley and Muna I. Naash},
  journal={Vision Research},
The use of nanoparticles as carriers for the delivery of therapeutic materials to target tissues has became popular in recent years and has demonstrated great potentials for the treatments of a wide range of diseases. In this review, we summarize the advantages of nanotechnology as a common gene delivery strategy with emphasis on ocular therapy. Particular attention is paid to the CK30-PEG compacted DNA nanoparticles that have been successfully tested in the eye, lung, and brain. These… CONTINUE READING

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