Nanoparticle PCR: nanogold-assisted PCR with enhanced specificity.

  title={Nanoparticle PCR: nanogold-assisted PCR with enhanced specificity.},
  author={Haikuo Li and Jiehuan Huang and Junhong Lv and Hongjie An and Xiaodong Zhang and Zhizhou Zhang and Chunhai Fan and Jun Hu},
  journal={Angewandte Chemie},
  volume={44 32},
The polymerase chain reaction (PCR) revolutionized molecular genetics and has become one of the most popular techniques in modern biological and medical sciences. Owing to the exponential amplification ability of PCR, one could start from even a single copy of target DNA to produce large amounts of DNA copies for sequencing, molecular diagnosis, or genetic analysis. This remarkable amplification ability is critical in many circumstances, such as earlystage diagnosis of HIV or cancers. Given the… CONTINUE READING