Nanoparticle-Mediated Target Delivery of TRAIL as Gene Therapy for Glioblastoma.

Abstract

Human tumor necrosis factor α-related apoptosis-inducing ligand (TRAIL) is an attractive cancer therapeutic because of its ability to induce apoptosis in tumor cells while having a negligible effect on normal cells. However, the short serum half-life of TRAIL and lack of efficient in vivo administration approaches have largely hindered its clinical use… (More)
DOI: 10.1002/adhm.201500563

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