Nanomolar Naloxone Attenuates Neurotoxicity Induced by Oxidative Stress and Survival Motor Neuron Protein Deficiency

Abstract

Oxidative stress and survival motor neuron (Smn) protein deficiency are the major causes of motor neuronal death. Naloxone exhibits neuroprotection against ischemic stroke and anti-inflammation. In this study, we determined whether nanomolar naloxone provides neuroprotection under oxidative stress (H2O2) and Smn deficiency in a motor neuron-like cell line… (More)
DOI: 10.1007/s12640-013-9414-3

Topics

6 Figures and Tables

Cite this paper

@article{Hsu2013NanomolarNA, title={Nanomolar Naloxone Attenuates Neurotoxicity Induced by Oxidative Stress and Survival Motor Neuron Protein Deficiency}, author={Ya-Yun Hsu and Yuh-Jyh Jong and Yu-Ting Lin and Yu-Ting Tseng and Shih-Hsien Hsu and Yi-Ching Lo}, journal={Neurotoxicity Research}, year={2013}, volume={25}, pages={262-270} }