Nanomedicines for ocular NSAIDs: safety on drug delivery.

  title={Nanomedicines for ocular NSAIDs: safety on drug delivery.},
  author={Joana Ara{\'u}jo and Elisabet Gonz{\'a}lez and Mar{\'i}a Antonia Egea and Marisa Luisa Garcia and E. Souto},
  journal={Nanomedicine : nanotechnology, biology, and medicine},
  volume={5 4},
UNLABELLED The eyes are among the most readily accessible organs in terms of location in the body, yet drug delivery to eye tissues is particularly problematic. Poor bioavailability of drugs from ocular dosage forms is mainly due to precorneal loss factors (e.g., tear dynamics, nonproductive absorption, transient residence time in the cul-de-sac, and relative impermeability of the corneal epithelial membrane). There is a clear need for effective topical formulations capable of promoting drug… CONTINUE READING