Nanomedicine against multidrug resistance in cancer treatment.

  title={Nanomedicine against multidrug resistance in cancer treatment.},
  author={Jie Gao and Si-shen Feng and Yajun Guo},
  volume={7 4},
Cancer is the leading cause of death in the world, accounting for 7.6 million deaths (~13% of all deaths) in 2008. Chemotherapy is widely used as a single-agent therapy or an adjuvant therapy in the management of cancer. Although effective, chemotherapy is subject to multidrug resistance (MDR) as a major obstacle [1]. MDR in cancer, referring to the ability of cancer cells to survive from treatment of a wide range of chemotherapeutics, is one of the most important problems in chemotherapy [1… CONTINUE READING