Nanomedicine: current status and future prospects

  title={Nanomedicine: current status and future prospects},
  author={S. Moein Moghimi and Alan Christy Hunter and J. C. Murray},
  journal={The FASEB Journal},
  pages={311 - 330}
Applications of nanotechnology for treatment, diagnosis, monitoring, and control of biological systems has recently been referred to as “nanomedicine” by the National Institutes of Health. Research into the rational delivery and targeting of pharmaceutical, therapeutic, and diagnostic agents is at the forefront of projects in nanomedicine. These involve the identification of precise targets (cells and receptors) related to specific clinical conditions and choice of the appropriate nanocarriers… 

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Current advances in nanomedicine raise exciting possibilities for future nanoparticle applications in personalized cancer therapy, and diagnostic agents and chemotherapeutic drugs can be integrated into their design for more efficient imaging and treatment of the tumor with fewer side effects.

Nanomedicines for Cancer Therapy: An Update of FDA Approved and Those under Various Stages of Development

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Nanomedicines for Cancer Therapy : An Update of FDA Approved and Those under Various Stages of Development

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New challenges in the use of nanomedicine in cancer therapy

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Nanotechnology Toward Treating Cancer

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Nanomedicine for respiratory diseases.

Surface-Engineered Cancer Nanomedicine: Rational Design And Recent Progress.

The physicochemical manipulation of cancer nanomedicine for rational design and recent progress in the area of surface engineering ofnanomedicines to improve the efficacy of cancer chemotherapeutics in MDR cancer as well are discussed.

A review of the current scientific and regulatory status of nanomedicines and the challenges ahead.

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Design and Function of a Dendrimer-Based Therapeutic Nanodevice Targeted to Tumor Cells Through the Folate Receptor

These results demonstrate the ability to design and produce polymer-based nanodevices for the intracellular targeting of drugs, imaging agents, and other materials.

Nanotech approaches to drug delivery and imaging.

Long-circulating and target-specific nanoparticles: theory to practice.

The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.

Nanocrystal targeting in vivo

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Probing the structural and molecular diversity of tumor vasculature.

Moving smaller in drug discovery and delivery

The emerging micro- and nanotechnology tools, techniques and devices that are being applied to advance the fields of drug discovery and drug delivery are highlighted.

Microparticles and nanoparticles as delivery systems for DNA vaccines.

    Z. CuiR. Mumper
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  • 2003
The application of microparticles and nanoparticles as DNA vaccine delivery systems will be critically reviewed with a primary focus on those systems that have generated in vivo immune responses.

In vivo cancer targeting and imaging with semiconductor quantum dots

Sensitive and multicolor fluorescence imaging of cancer cells under in vivo conditions are achieved and a whole-body macro-illumination system with wavelength-resolved spectral imaging is integrated for efficient background removal and precise delineation of weak spectral signatures.

Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function.

    R. Jain
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