Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells

@article{Anderson2004NanoliterscaleSO,
  title={Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells},
  author={Daniel G Anderson and Shulamit Levenberg and Robert Langer},
  journal={Nature Biotechnology},
  year={2004},
  volume={22},
  pages={863-866}
}
Identification of biomaterials that support appropriate cellular attachment, proliferation and gene expression patterns is critical for tissue engineering and cell therapy. Here we describe an approach for rapid, nanoliter-scale synthesis of biomaterials and characterization of their interactions with cells. We simultaneously characterize over 1,700 human embryonic stem cell–material interactions and identify a host of unexpected materials effects that offer new levels of control over human… CONTINUE READING