Nanogap-engineerable Raman-active nanodumbbells for single-molecule detection.

  title={Nanogap-engineerable Raman-active nanodumbbells for single-molecule detection.},
  author={Dong-Kwon Lim and Ki-Seok Jeon and Hyung Min Kim and Jwa-Min Nam and Yung Doug Suh},
  journal={Nature materials},
  volume={9 1},
Surface-enhanced Raman scattering (SERS)-based signal amplification and detection methods using plasmonic nanostructures have been widely investigated for imaging and sensing applications. However, SERS-based molecule detection strategies have not been practically useful because there is no straightforward method to synthesize and characterize highly sensitive SERS-active nanostructures with sufficiently high yield and efficiency, which results in an extremely low cross-section area in Raman… CONTINUE READING