• Biology, Medicine
• Published in
  Journal of tissue engineering…
  2018
• DOI:10.1002/term.2353

Nanofibrous gelatine scaffolds integrated with nerve growth factor-loaded alginate microspheres for brain tissue engineering.

@article{Bykz2018NanofibrousGS,
  title={Nanofibrous gelatine scaffolds integrated with nerve growth factor-loaded alginate microspheres for brain tissue engineering.},
  author={Melda B{\"u}y{\"u}k{\"o}z and Esra Erdal and Sacide Alsoy Altinkaya},
  journal={Journal of tissue engineering and regenerative medicine},
  year={2018},
  volume={12 2},
  pages={
          e707-e719
        }
}

• Melda Büyüköz, Esra Erdal, Sacide Alsoy Altinkaya

Neural regeneration research is designed in part to develop strategies for therapy after nerve damage due to injury or disease. In this study, a new gelatine-based biomimetic scaffold was fabricated for brain tissue engineering applications. A technique combining thermally induced phase separation and porogen leaching was used to create interconnected macropores and nanofibrous structure. To promote tissue regeneration processes, the scaffolds were integrated with nerve growth factor (NGF… CONTINUE READING

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