• Biology, Medicine
  • Published in
    Journal of tissue engineering…
    2018
  • DOI:10.1002/term.2353

Nanofibrous gelatine scaffolds integrated with nerve growth factor-loaded alginate microspheres for brain tissue engineering.

@article{Bykz2018NanofibrousGS,
  title={Nanofibrous gelatine scaffolds integrated with nerve growth factor-loaded alginate microspheres for brain tissue engineering.},
  author={Melda B{\"u}y{\"u}k{\"o}z and Esra Erdal and Sacide Alsoy Altinkaya},
  journal={Journal of tissue engineering and regenerative medicine},
  year={2018},
  volume={12 2},
  pages={
          e707-e719
        }
}
Neural regeneration research is designed in part to develop strategies for therapy after nerve damage due to injury or disease. In this study, a new gelatine-based biomimetic scaffold was fabricated for brain tissue engineering applications. A technique combining thermally induced phase separation and porogen leaching was used to create interconnected macropores and nanofibrous structure. To promote tissue regeneration processes, the scaffolds were integrated with nerve growth factor (NGF… CONTINUE READING

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SHOWING 1-10 OF 45 REFERENCES

Protein crosslinking method

  • GT Hermanson
  • In Bioconjugate Techniques, Hermanson GT (ed). Academic Press: San Diego,
  • 1996
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Phase separation, pore structure, and properties of nanofibrous gelatin scaffolds.

VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Substrate modulus directs neural stem cell behavior.

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Bioengineered functional brain-like cortical tissue.

VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Neurite Outgrowth on a DNA Crosslinked Hydrogel with Tunable Stiffnesses

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Studies of formation of W/O nano-emulsions

VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL

Neural tissue engineering: strategies for repair and regeneration.

VIEW 1 EXCERPT
HIGHLY INFLUENTIAL

THE EFFECT OF pH ON GROWTH, PROTEIN SYNTHESIS, AND LIPID-RICH PARTICLES OF CULTURED MAMMALIAN CELLS

VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL