Nanofibrillar scaffolds induce preferential activation of Rho GTPases in cerebral cortical astrocytes

  title={Nanofibrillar scaffolds induce preferential activation of Rho GTPases in cerebral cortical astrocytes},
  author={Volkan Mujdat Tiryaki and Virginia M. Ayres and Adeel A Khan and Ijaz Ahmed and David I Shreiber and Sally Meiners},
  booktitle={International journal of nanomedicine},
Cerebral cortical astrocyte responses to polyamide nanofibrillar scaffolds versus poly-L-lysine (PLL)-functionalized planar glass, unfunctionalized planar Aclar coverslips, and PLL-functionalized planar Aclar surfaces were investigated by atomic force microscopy and immunocytochemistry. The physical properties of the cell culture environments were evaluated using contact angle and surface roughness measurements and compared. Astrocyte morphological responses, including filopodia, lamellipodia… CONTINUE READING
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