Nanofibers containing tetracycline/β-cyclodextrin: Physico-chemical characterization and antimicrobial evaluation.

@article{Monteiro2017NanofibersCT,
  title={Nanofibers containing tetracycline/β-cyclodextrin: Physico-chemical characterization and antimicrobial evaluation.},
  author={Ana Paula F. S. Monteiro and C{\'i}ntia M S L Rocha and Michele F Oliveira and Savio Morato Lacerda Gontijo and Ricardo R Agudelo and Rub{\'e}n D{\'a}rio Sinisterra and Mar{\'i}a Esperanza Cort{\'e}s},
  journal={Carbohydrate polymers},
  year={2017},
  volume={156},
  pages={
          417-426
        }
}
This study aimed to compare two nanofiber drug delivery systems that were prepared with an electrospun process and have the potential to serve as adjuvants for the treatment of periodontal disease. The first system was composed of polycaprolactone loaded with tetracycline (TCN) and the second was composed of polycaprolactone loaded with tetracycline/β-cyclodextrin (TCN:BCD). An antimicrobial diffusion test was performed for each of these sets of nanofibers with the microorganisms… CONTINUE READING