Nanofiber technology in the ex vivo expansion of cord blood-derived hematopoietic stem cells.

@article{Ferreira2018NanofiberTI,
  title={Nanofiber technology in the ex vivo expansion of cord blood-derived hematopoietic stem cells.},
  author={Monica S Ventura Ferreira and Seyed Hadi Mousavi},
  journal={Nanomedicine : nanotechnology, biology, and medicine},
  year={2018},
  volume={14 5},
  pages={
          1707-1718
        }
}
Umbilical cord blood (CB) can be used as an alternative source of hematopoietic stem cells (HSCs) for transplantation in hematological and non-hematological disorders. Despite several recognized advantages the limited cell number in CB one unit still restricts its clinical use. The success of transplantation greatly depends on the levels of total nucleated cell and CD34+ cell counts. Thus, many ex vivo strategies have been developed within the last decade in order to solve this obstacle, with… CONTINUE READING
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