Nanocarriers with multi-locked DNA valves targeting intracellular tumor-related mRNAs for controlled drug release.

Abstract

The fabrication of well-behaved drug delivery systems that can transport drugs to specifically treat cancer cells rather than normal cells is still a tremendous challenge. A novel drug delivery system with two types of tumor-related mRNAs as "keys" to open the multiple valves of the nanocarrier to control drug release was developed. Hollow mesoporous silica… (More)
DOI: 10.1039/c7nr06479a

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