Nanocarriers’ entry into the cell: relevance to drug delivery

  title={Nanocarriers’ entry into the cell: relevance to drug delivery},
  author={Herv{\'e} Hillaireau and Patrick Couvreur},
  journal={Cellular and Molecular Life Sciences},
Nanocarriers offer unique possibilities to overcome cellular barriers in order to improve the delivery of various drugs and drug candidates, including the promising therapeutic biomacromolecules (i.e., nucleic acids, proteins). There are various mechanisms of nanocarrier cell internalization that are dramatically influenced by nanoparticles’ physicochemical properties. Depending on the cellular uptake and intracellular trafficking, different pharmacological applications may be considered. This… CONTINUE READING
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