Nanocarrier-mediated drugs targeting cancer stem cells: an emerging delivery approach.

@article{Malhi2015NanocarriermediatedDT,
  title={Nanocarrier-mediated drugs targeting cancer stem cells: an emerging delivery approach.},
  author={Sarandeep Singh Malhi and Xiaochen Gu},
  journal={Expert opinion on drug delivery},
  year={2015},
  volume={12 7},
  pages={
          1177-201
        }
}
INTRODUCTION Cancer stem cells (CSCs) play an important role in the development of drug resistance, metastasis and recurrence. Current conventional therapies do not commonly target CSCs. Nanocarrier-based delivery systems targeting cancer cells have entered a new era of treatment, where specific targeting to CSCs may offer superior outcomes to efficient cancer therapies. AREAS COVERED This review discusses the involvement of CSCs in tumor progression and relevant mechanisms associated with… CONTINUE READING
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