Nanobodies as novel agents for disease diagnosis and therapy

@inproceedings{Siontorou2013NanobodiesAN,
  title={Nanobodies as novel agents for disease diagnosis and therapy},
  author={Christina G. Siontorou},
  booktitle={International journal of nanomedicine},
  year={2013}
}
The discovery of naturally occurring, heavy-chain only antibodies in Camelidae, and their further development into small recombinant nanobodies, presents attractive alternatives in drug delivery and imaging. Easily expressed in microorganisms and amenable to engineering, nanobody derivatives are soluble, stable, versatile, and have unique refolding capacities, reduced aggregation tendencies, and high-target binding capabilities. This review outlines the current state of the art in nanobodies… CONTINUE READING
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