Nanobiotechnology-based strategies for crossing the blood-brain barrier.

@article{Jain2012NanobiotechnologybasedSF,
  title={Nanobiotechnology-based strategies for crossing the blood-brain barrier.},
  author={Kewal K. Jain},
  journal={Nanomedicine},
  year={2012},
  volume={7 8},
  pages={1225-33}
}
The blood-brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been employed to deliver drugs across this barrier and some of these may do structural damage to the BBB by forcibly opening it to allow the uncontrolled passage of drugs. The ideal method for transporting drugs across the BBB should be controlled and should not damage the barrier. Among the various approaches… CONTINUE READING

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