Naltrexone and nalmefene attenuate cocaine place preference in male mice

@article{Windisch2018NaltrexoneAN,
  title={Naltrexone and nalmefene attenuate cocaine place preference in male mice},
  author={K. Windisch and B. Reed and M. Kreek},
  journal={Neuropharmacology},
  year={2018},
  volume={140},
  pages={174-183}
}
Abstract Cocaine addiction treatment is difficult due to the current lack of approved pharmacotherapuetics. Several preclinical and clinical studies have demonstrated that the mu opioid receptor (MOPr) antagonist/kappa opioid receptor (KOPr) partial agonist naltrexone (NTX) reduces the subjective effects and self‐administration of cocaine. However, very limited research has examined the ability of the structurally similar MOPr antagonist/KOPr partial agonist nalmefene (NMF) to reduce cocaine… Expand
Endogenous Opiates and Behavior: 2018
Five Decades of Research on Opioid Peptides: Current Knowledge and Unanswered Questions
The Laboratory of the Biology of Addictive Diseases: Four Women in Neuroscience

References

SHOWING 1-10 OF 80 REFERENCES
Intravenous cocaine challenges during naltrexone maintenance: A preliminary study
Opioidergic modulation of cocaine conditioned place preferences.
Treatment of cocaine craving with as-needed nalmefene, a partial κ opioid receptor agonist: first clinical experience.
Effects of naltrexone and isradipine, alone or in combination, on cocaine responses in humans
...
1
2
3
4
5
...