Naltrexone, an opioid blocker, alters taste perception and nutrient intake in humans.

@article{Bertino1991NaltrexoneAO,
  title={Naltrexone, an opioid blocker, alters taste perception and nutrient intake in humans.},
  author={M. G. Bertino and Gary K. Beauchamp and Karl Engelman},
  journal={The American journal of physiology},
  year={1991},
  volume={261 1 Pt 2},
  pages={R59-63}
}
To test the hypothesis that reduced food intake produced by opioid blockade is due to a reduction in the pleasant aspects of tastes, 18 fasted male college students rated the intensity and pleasantness of soup that contained various concentrations of NaCl and of Kool-Aid that contained various concentrations of sucrose at hourly intervals after ingesting either naltrexone (50 mg) or a placebo in a double-blind study. Hunger, fullness, nausea, and current mood state were also assessed. Lunch… CONTINUE READING
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